Mei Mio was one of the female students at Akademi High School in Yandere Simulator.
Mei had indigo blue hair with bangs falling on her face worn in a small bun. There was also an ahoge sticking out from the top of her head. Her eye colour matches her hair colour. Mei's bust size is 1.4. She used to wear the white sailor uniform, unless customized by the player. She also had blue stockings matching her blue panties, a blue friendship bracelet on her wright wrist, as well as blue framed glasses.
Mei Mio has the Teacher's Pet persona. If she witnesses murder or finds a corpse, she will report it to her homeroom teacher. Mei reacts to a camera pointed at her by giving a supsicious look.
- Mei's hairstyle before the February 8th, 2016 Build was changed because YandereDev thought that her previous hairstyle was "low budget" and "amateurish".
- Along with Ryusei Koki, Mei is the only one in the Rainbow 12 group to have the "Teacher's Pet" trait.
- Originally, Mei Mio's name was Tsumu Kotobo.
- Like all other students, Mei Mio recieves a different appearance in the Lovesick Mode. In it, Mei's indigo colours are replaced with black - her hair, eyes, stockings, panties, friendship bracelet and glasses are all black with a very slight tint of blue.